Review · 2015
GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration
Pickart L, Margolina A. · BioMed Research International
Synthesizes gene-expression work showing GHK-Cu modulates over 4,000 human genes toward a younger transcriptional profile, alongside small clinical dermatology results.
Key findings
- Stimulates collagen, elastin, decorin, and glycosaminoglycan synthesis
- Antioxidant and anti-inflammatory activity
- Improved skin density in controlled topical trials
Limitations
Review authored by the compound's principal researcher; clinical trials are small and industry-linked.