Reference

Peptide Library

12 profiles covering mechanism of action, half-life, the doses used in published studies, reported adverse effects, and current regulatory status. Every entry carries an evidence grade so preclinical work is never presented as clinical proof.

Semaglutide

Metabolic · t½ ~7 days

FDA-approved

A long-acting GLP-1 receptor agonist and the most rigorously studied weight-management peptide in modern medicine, with cardiovascular outcome data from tens of thousands of patients.

aka Ozempic, Wegovy, Rybelsus

Tirzepatide

Metabolic · t½ ~5 days

FDA-approved

A dual GIP/GLP-1 receptor agonist that produced the largest weight reductions ever recorded for a non-surgical intervention in randomized trials.

aka Mounjaro, Zepbound

BPC-157

Repair & Recovery · t½ ~4 hours (rodent data)

Preclinical

A synthetic pentadecapeptide derived from human gastric juice protein BPC, with an extensive rodent literature on tendon, ligament, gut, and nerve healing — and almost no controlled human data.

aka Body Protection Compound 157, Pentadecapeptide BPC 157

TB-500 (Thymosin Beta-4 Fragment)

Repair & Recovery · t½ ~2–3 hours (estimated)

Phase II

A synthetic fragment of the actin-sequestering protein thymosin beta-4, studied in cardiac repair and corneal/dermal wound healing, and heavily used off-label in veterinary and grey-market human settings.

aka TB4 fragment, Tβ4 17-23

CJC-1295 + Ipamorelin

Growth Hormone · t½ CJC-1295 (DAC): ~6–8 days; Ipamorelin: ~2 hours

Phase I

The most common growth-hormone secretagogue pairing: a GHRH analogue combined with a selective ghrelin-receptor agonist, intended to raise endogenous GH pulses rather than inject exogenous GH.

aka Mod GRF 1-29 stack, GHRH + ghrelin mimetic

Tesamorelin

Growth Hormone · t½ ~26–38 minutes

FDA-approved

The only FDA-approved GHRH analogue, indicated for HIV-associated lipodystrophy, and one of the few peptides with randomized evidence for visceral-fat reduction and liver-fat improvement.

aka Egrifta

Semax

Cognitive · t½ Minutes (intranasal, rapid CNS uptake)

Phase II

A heptapeptide ACTH fragment approved in Russia for stroke and cognitive indications, with essentially no Western regulatory recognition and a modest but real clinical literature.

aka ACTH(4-10) analogue, Met-Glu-His-Phe-Pro-Gly-Pro

Epitalon

Longevity · t½ Very short (minutes)

Preclinical

A synthetic tetrapeptide from the Russian gerontology literature, claimed to modulate telomerase and pineal melatonin rhythms, with long-term mortality data that has never been independently replicated.

aka Epithalon, AEDG peptide

Thymosin Alpha-1

Immune · t½ ~2 hours

Phase III

An immunomodulating thymic peptide approved in more than 30 countries for hepatitis B/C and used as an adjuvant in sepsis and oncology settings, though not FDA-approved.

aka Tα1, Zadaxin

GHK-Cu

Repair & Recovery · t½ N/A (topical use)

Phase II

A copper-binding tripeptide present in human plasma and the best-supported cosmetic peptide, with in-vitro and small clinical evidence for collagen synthesis and skin remodeling.

aka Copper tripeptide-1, Gly-His-Lys copper

Retatrutide

Metabolic · t½ ~6 days

Phase III

An investigational triple agonist of GIP, GLP-1, and glucagon receptors that produced roughly 24% weight loss at 48 weeks in Phase II — the highest figure yet reported for a pharmacologic agent.

aka LY3437943, triple-G agonist

PT-141 (Bremelanotide)

Metabolic · t½ ~2.7 hours

FDA-approved

A melanocortin receptor agonist approved for hypoactive sexual desire disorder in premenopausal women — a rare case of a 'lifestyle' peptide clearing full FDA review.

aka Vyleesi, bremelanotide