RCT · 2011
Semax in Acute Ischemic Stroke: Neurological Recovery Outcomes
Gusev EI, Skvortsova VI, et al. · Zhurnal Nevrologii i Psikhiatrii
Russian trials report improved neurological scores when intranasal Semax is added to standard stroke care within the acute window.
Key findings
- Faster NIHSS improvement versus control
- Reduced infarct-zone markers on imaging
- Good tolerability at studied doses
Limitations
Blinding and randomization reporting are limited, results are single-region, and no Western replication exists.